Multifunctional electrospinning composite fibers for orthotopic cancer treatment in vivo

	Multifunctional electrospinning composite fibers for orthotopic cancer treatment in vivo
	Chen,Yinyin; Liu,Shi; Hou,Zhiyao; Ma,Pingan; Yang,Dongmei; Li,Chunxia; Li,Jun
刊名	nano research
	2015
卷号	8 期号:6 页码:1917-1931
关键词	MESOPOROUS SILICA NANOPARTICLES UP-CONVERSION NANOPARTICLES DRUG-DELIVERY SYSTEMS PHOTODYNAMIC THERAPY PHOTOTHERMAL THERAPY RELEASE NANOPROBES SCAFFOLD POLYMER TUMOR
通讯作者	li,cx
英文摘要	a multifunctional, dual-drug carrier platform was successfully constructed. core-shell structured nagdf4:yb/er@ nagdf4:yb@msio(2)-polyethylene glycol (abbreviated as ucnps) nanoparticles loaded with the antitumor drug, doxorubicin (dox) were incorporated into poly(epsilon-caprolactone) (pcl) and gelatin loaded with antiphlogistic drug, indomethacin (mc) to form nanofibrous fabrics (labeled as mc/ucnps/dox) via electrospinning process. the resultant multifunctional spinning pieces can be surgically implanted directly at the tumor site of mice as an orthotopic chemotherapy by controlled-release dox from mesoporous silicon dioxide (sio2) and upconversion fluorescence/magnetic resonance dual-model imaging through nagdf4:yb/er@nagdf4:yb embedded in mc/ucnps/dox in vivo.
收录类别	SCI
语种	英语
WOS记录号	WOS:000358051300012
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/64684]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Chen,Yinyin,Liu,Shi,Hou,Zhiyao,et al. Multifunctional electrospinning composite fibers for orthotopic cancer treatment in vivo[J]. nano research,2015,8(6):1917-1931.
APA	Chen,Yinyin.,Liu,Shi.,Hou,Zhiyao.,Ma,Pingan.,Yang,Dongmei.,...&Li,Jun.(2015).Multifunctional electrospinning composite fibers for orthotopic cancer treatment in vivo.nano research,8(6),1917-1931.
MLA	Chen,Yinyin,et al."Multifunctional electrospinning composite fibers for orthotopic cancer treatment in vivo".nano research 8.6(2015):1917-1931.