Determination of synthetic phenolic antioxidants and relative metabolites in sewage treatment plant and recipient river by high performance liquid chromatography-electrospray tandem mass spectrometry

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Determination of synthetic phenolic antioxidants and relative metabolites in sewage treatment plant and recipient river by high performance liquid chromatography-electrospray tandem mass spectrometry
	Liu, Runzeng; Ruan, Ting; Song, Shanjun; Lin, Yongfeng; Jiang, Guibin
刊名	JOURNAL OF CHROMATOGRAPHY A
	2015-02-13
卷号	1381 期号:1 页码:13-21
关键词	Synthetic phenolic antioxidants Metabolites Liquid chromatography-tandem mass spectrometry Sludge Sewage effluent Recipient river
英文摘要	Robust analytical methods were developed for the determination of eight emerging synthetic phenolic antioxidants (SPAs) and three metabolites in sewage sludge, effluent and river water matrices. Accelerated solvent extraction was employed for the extraction of the target analytes from sludge, dichloromethane/hexane =3:1 (extraction solvent) and 90 degrees C (extraction temperature) were used after optimization. Silica gel packed column Was chosen for the subsequent cleanup procedure for sludge extract. For the water sample analysis, liquid-liquid extraction combined with silica gel clean-up was used. The targets were determined by optimized high performance liquid chromatography-tandem mass spectrometry method in negative electrospray ionization mode. The method quantification limits of the 11 analytes ranged from 0.1 to 23 ng/L, 0.1 to 20 ng/L and 0.1 to 15 ng/g for sewage effluent, river water and sludge matrices, respectively. The total recoveries of the pretreatment varied from 63 to 106%, with relative standard deviations less than 17% for the three matrices at different spiking levels. Nine targets including 2,6-di-tert-butyl-4-methylphenol (BHT), 3,5-di-tert-butyl-4-hydroxybenzaldehyde (BHT-CHO), 2,6di-tert-butyl-1,4-benzoquinone (BHT-Q), 2,6-di-tert-butyl-4-hydroxy-4-methyl-2,5-cyclohexadienone (BHT-quinol), 3-tert-butyl-4-hydroxyanisole (BHA), 4-tert-octylphenol (4-tOP), 2,2'-methylenebis(6-tert-butyl-4-methylphenol) (AO 2246), 4,4'-butylidenebis(2-(1,1-dimethylethyl)-5-methyl-phenol) (AO 44B25) and 1,3,5-trimethyl-2,4,6-tris(3,5-di-tert-butyl-4-hydroxybenzyl)benzene (AO 330) were identified in the collected samples, with concentrations ranging 1.1-2325 ng/g and 0.4-2510 ng/L for sludge and water matrices, respectively. Sewage effluent was considered as a possible contamination source of certain SPA homologues and relative metabolites to the recipient aquatic systems. (C) 2015 Published by Elsevier B.V.
研究领域[WOS]	Biochemical Research Methods ; Chemistry, Analytical
WOS记录号	WOS:000349590600002
公开日期	2016-03-15
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/32551]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Liu, Runzeng,Ruan, Ting,Song, Shanjun,et al. Determination of synthetic phenolic antioxidants and relative metabolites in sewage treatment plant and recipient river by high performance liquid chromatography-electrospray tandem mass spectrometry[J]. JOURNAL OF CHROMATOGRAPHY A,2015,1381(1):13-21.
APA	Liu, Runzeng,Ruan, Ting,Song, Shanjun,Lin, Yongfeng,&Jiang, Guibin.(2015).Determination of synthetic phenolic antioxidants and relative metabolites in sewage treatment plant and recipient river by high performance liquid chromatography-electrospray tandem mass spectrometry.JOURNAL OF CHROMATOGRAPHY A,1381(1),13-21.
MLA	Liu, Runzeng,et al."Determination of synthetic phenolic antioxidants and relative metabolites in sewage treatment plant and recipient river by high performance liquid chromatography-electrospray tandem mass spectrometry".JOURNAL OF CHROMATOGRAPHY A 1381.1(2015):13-21.