Development of Ar-BINMOL-Derived Atropisomeric Ligands with Matched Axial and sp(3) Central Chirality for Catalytic Asymmetric Transformations | |
Xu, Zheng1; Xu LW(徐利文)1,2 | |
刊名 | Chemical Record |
2015 | |
卷号 | 15期号:5页码:925-948 |
关键词 | asymmetric catalysis atropisomerism BINOLs chirality Wittig rearrangements |
ISSN号 | 1527-8999 |
通讯作者 | 徐利文 |
英文摘要 | Recently, academic chemists have renewed their interest in the development of 1,1′-binaphthalene-2,2′-diol (BINOL)-derived chiral ligands. Six years ago, a working hypothesis, that the chirality matching of hybrid chirality on a ligand could probably lead to high levels of stereoselective induction, prompted us to use the axial chirality of BINOL derivatives to generate new stereogenic centers within the same molecule with high stereoselectivity, obtaining as a result sterically favorable ligands for applications in asymmetric catalysis. This Personal Account describes our laboratory's efforts toward the development of a novel class of BINOL-derived atropisomers bearing both axial and sp3 central chirality, the so-called Ar-BINMOLs, for asymmetric synthesis. Furthermore, on the basis of the successful application of Ar-BINMOLs and their derivatives in asymmetric catalysis, the search for highly efficient and enantioselective processes also compelled us to give special attention to the BINOL-derived multifunctional ligands with multiple stereogenic centers for use in catalytic asymmetric reactions. |
学科主题 | 物理化学与绿色催化 |
收录类别 | SCI |
资助信息 | the National Natural Science Foundation of China (No. 21173064;21472031);the Zhejiang Provincial Natural Science Foundation of China (LR14B030001) |
语种 | 英语 |
WOS记录号 | WOS:000364313400006 |
内容类型 | 期刊论文 |
源URL | [http://210.77.64.217/handle/362003/19078] |
专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
作者单位 | 1.Hangzhou Normal Univ, Key Lab Organosilicon Chem & Mat Technol, Minist Educ, Hangzhou, Zhejiang, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
推荐引用方式 GB/T 7714 | Xu, Zheng,Xu LW. Development of Ar-BINMOL-Derived Atropisomeric Ligands with Matched Axial and sp(3) Central Chirality for Catalytic Asymmetric Transformations[J]. Chemical Record,2015,15(5):925-948. |
APA | Xu, Zheng,&Xu LW.(2015).Development of Ar-BINMOL-Derived Atropisomeric Ligands with Matched Axial and sp(3) Central Chirality for Catalytic Asymmetric Transformations.Chemical Record,15(5),925-948. |
MLA | Xu, Zheng,et al."Development of Ar-BINMOL-Derived Atropisomeric Ligands with Matched Axial and sp(3) Central Chirality for Catalytic Asymmetric Transformations".Chemical Record 15.5(2015):925-948. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论