Chemical constituents from Euphorbia wallichii and their biological activities

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 资源植物与生物技术所级重点实验室

	Chemical constituents from Euphorbia wallichii and their biological activities
	Yang,Da-Song; Peng,Wei-Bing; Yang,Yong-Ping; Liu,Ke-Chun; Li,Xiao-Li; Xiao,Wei-Lie
刊名	JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
	2015-09-02
卷号	17 期号:9 页码:946-951
关键词	Euphorbia wallichii diterpenoid wallichiioid A cytotoxicity antiangiogenic activities
英文摘要	One rare diterpenoid which was an unusual phorbol derivative possessing a 5-ene-7-oxo functional group, wallichiioid A (1), and 17 known compounds (2-18) were isolated from the aerial parts of Euphorbia wallichii. The structures and relative configuration of these compounds were elucidated on the basis of extensive spectroscopic interpretation. All the known compounds were isolated from E. wallichii for the first time. Diterpenoids 1-5 were tested for their cytotoxicity against five cancer cell lines (A-549, MCF-7, Hep G2, HeLa, and P388) and showed IC50 values in the range of 8.19-29.72g/mL. The antiangiogenic activities of diterpenoids 1-5 were also evaluated using a zebrafish model.
类目[WOS]	Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]	Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]	PHORBOL ESTERS ; DITERPENOIDS
收录类别	SCI
语种	英语
WOS记录号	WOS:000361969800010
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/25165]
专题	昆明植物研究所_资源植物与生物技术所级重点实验室
推荐引用方式 GB/T 7714	Yang,Da-Song,Peng,Wei-Bing,Yang,Yong-Ping,et al. Chemical constituents from Euphorbia wallichii and their biological activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2015,17(9):946-951.
APA	Yang,Da-Song,Peng,Wei-Bing,Yang,Yong-Ping,Liu,Ke-Chun,Li,Xiao-Li,&Xiao,Wei-Lie.(2015).Chemical constituents from Euphorbia wallichii and their biological activities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,17(9),946-951.
MLA	Yang,Da-Song,et al."Chemical constituents from Euphorbia wallichii and their biological activities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 17.9(2015):946-951.