Penchinones A-D, two pairs of cis-trans isomers with rearranged neolignane carbon skeletons from Penthorum chinense

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Penchinones A-D, two pairs of cis-trans isomers with rearranged neolignane carbon skeletons from Penthorum chinense
	He, Ya-Cong 1,2; Peng, Cheng 1,2; Xie, Xiao-Fang 1,2; Chen, Ming-Hua 3,4; Li, Xiao-Nian 5; Li, Meng-Ting 1,2; Zhou, Qin-Mei 1,2; Guo, Li 1,2; Xiong, Liang 1,2
刊名	RSC ADVANCES
	2015
卷号	5 期号:94 页码:76788-76794
英文摘要	Penchinones A-D (1-4), two pairs of novel cis-trans lignan isomers with rearranged neolignane carbon skeletons, together with six known flavonoids (5-10), were isolated from the ethyl acetate-soluble portion of a hepatoprotective water decoction of Penthorum chinense. Their structures were determined by extensive spectroscopic data analysis, ECD calculation, and single-crystal X-ray diffraction. Penchinones C and D (3 and 4) featured an unprecedented 7,30-neolignane carbon skeleton. Penchinone A (1) exhibited protective activity against acetaminophen-induced damage to the HL7702 hepatocyte and selective cytotoxicity against the human cancer ovarian cell line, Hey, in vitro.
类目[WOS]	Chemistry, Multidisciplinary
研究领域[WOS]	Chemistry
关键词[WOS]	CHEMISTRY ; LIGNANS ; ANTITUMOR ; LEAVES
收录类别	SCI
语种	英语
WOS记录号	WOS:000361559700018
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/25151]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chengdu Univ Tradit Chinese Med, State Key Lab Breeding Base Systemat Res Dev & Ut, Chengdu 611137, Peoples R China 2.Chengdu Univ Tradit Chinese Med, Sch Pharm, Chengdu 611137, Peoples R China 3.Chinese Acad Med Sci, Inst Med Biotechnol, Beijing 100050, Peoples R China 4.Peking Union Med Coll, Beijing 100050, Peoples R China 5.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
推荐引用方式 GB/T 7714	He, Ya-Cong,Peng, Cheng,Xie, Xiao-Fang,et al. Penchinones A-D, two pairs of cis-trans isomers with rearranged neolignane carbon skeletons from Penthorum chinense[J]. RSC ADVANCES,2015,5(94):76788-76794.
APA	He, Ya-Cong.,Peng, Cheng.,Xie, Xiao-Fang.,Chen, Ming-Hua.,Li, Xiao-Nian.,...&Xiong, Liang.(2015).Penchinones A-D, two pairs of cis-trans isomers with rearranged neolignane carbon skeletons from Penthorum chinense.RSC ADVANCES,5(94),76788-76794.
MLA	He, Ya-Cong,et al."Penchinones A-D, two pairs of cis-trans isomers with rearranged neolignane carbon skeletons from Penthorum chinense".RSC ADVANCES 5.94(2015):76788-76794.