A novel C-25 sterol peroxide from the endophytic fungus Phoma sp EA-122 | |
Chen, Zi-Ming2; Fan, Qiong-Ying3; Chen, He-Ping1,4; Li, Zheng-Hui1; Feng, Tao1; Liu, Ji-Kai1 | |
刊名 | ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES |
2015-03-01 | |
卷号 | 70期号:3-4页码:93-96 |
关键词 | C-25 sterol peroxide endophytic fungus Phoma sp. protein-tyrosine phosphatase |
英文摘要 | A novel C-25 sterol peroxide, phomasterol A (1), together with two known compounds (2-3), was isolated from the endophytic fungus Phoma sp. EA-122. The structure of phomasterol A (1) was elucidated by MS, 1D, and 2D NMR data analyses. Phomasterol A (1) was evaluated for its inhibitory activities against protein-tyrosine phosphatases MEG2 and PTP1Bc, showing moderate activities with identical IC50 values of 25 mu M. |
类目[WOS] | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy |
研究领域[WOS] | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy |
关键词[WOS] | INHIBITOR ; PHOSPHATASE |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000359347200008 |
公开日期 | 2016-02-26 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn/handle/151853/25093] |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Lingnan Normal Univ, Sch Chem & Chem Engn, Zhanjiang, Peoples R China 3.Hebei Normal Univ, Coll Life Sci, Shijiazhuang, Peoples R China 4.Univ Chinese Acad Sci, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Chen, Zi-Ming,Fan, Qiong-Ying,Chen, He-Ping,et al. A novel C-25 sterol peroxide from the endophytic fungus Phoma sp EA-122[J]. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES,2015,70(3-4):93-96. |
APA | Chen, Zi-Ming,Fan, Qiong-Ying,Chen, He-Ping,Li, Zheng-Hui,Feng, Tao,&Liu, Ji-Kai.(2015).A novel C-25 sterol peroxide from the endophytic fungus Phoma sp EA-122.ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES,70(3-4),93-96. |
MLA | Chen, Zi-Ming,et al."A novel C-25 sterol peroxide from the endophytic fungus Phoma sp EA-122".ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES 70.3-4(2015):93-96. |
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