Novel 2-arylbenzofuran dimers and polyisoprenylated flavanones from Sophora tonkinensis

	Novel 2-arylbenzofuran dimers and polyisoprenylated flavanones from Sophora tonkinensis
	Luo, Guoyong ; Yang, Yun ; Zhou, Min ; Ye, Qi ; Liu, Yan ; Gu, Jian ; Zhang, Guolin ; Luo, Yinggang
刊名	FITOTERAPIA
	2014
卷号	99 页码:21-27
关键词	Sophora tonkinensis Shandougenine 2-Arylbenzofuran Flavanone Antioxidant
通讯作者	Luo, YG (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Ctr Nat Prod Res, 9 Sect 4,Renmin Rd South, Chengdu 610041, Peoples R China.
产权排序	1
合作状况	其它
英文摘要	Two novel 2-arylbenzofuran dimers, shandougenines A (1) and B (2), and two new polyisoprenylated flavanones 3 (shandougenine C) and 4 (shandougenine D) were isolated from the 95% EtOH extract of Sophora tonkinensis, together with 18 known compounds. Their structures were determined on the basis of spectral data interpretation and by comparing the spectral data with that reported previously for known compounds. Shandougenine A (1) is a unique dimeric 2-arylbenzofuran with a C-3-C-5''' bond linkage. Shandougenine B (2) is the first naturally occurring dimeric 2-arylbenzofuran with a novel C-3-C-3 '' bond linkage. Compound 1 showed moderate DPPH free radical scavenging capacity, whereas 2 has stronger DPPH free radical and ABTS cation radical scavenging capacity than Vc. Compounds 12, 19, and 20 showed parallel DPPH free radical scavenging capacity with Vc. Compounds 1, 3, 4, 19, 20, and 22 have parallel ABTS cation radical scavenging capacity to Vc. Compounds 1, 3, 4, and 18 showed slightly stronger superoxide anion radical scavenging capacity than the known flavanone luteolin. The antioxidant activities of shandougenines A (1) and B (2) indicated that compounds 1 and 2 may represent novel scaffolds for the development of new antioxidants. (C) 2014 Elsevier B.V. All rights reserved.
学科主题	Chemistry, Medicinal; Pharmacology & Pharmacy
收录类别	SCI
语种	英语
公开日期	2016-02-26
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/26657]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Luo, Guoyong,Yang, Yun,Zhou, Min,et al. Novel 2-arylbenzofuran dimers and polyisoprenylated flavanones from Sophora tonkinensis[J]. FITOTERAPIA,2014,99:21-27.
APA	Luo, Guoyong.,Yang, Yun.,Zhou, Min.,Ye, Qi.,Liu, Yan.,...&Luo, Yinggang.(2014).Novel 2-arylbenzofuran dimers and polyisoprenylated flavanones from Sophora tonkinensis.FITOTERAPIA,99,21-27.
MLA	Luo, Guoyong,et al."Novel 2-arylbenzofuran dimers and polyisoprenylated flavanones from Sophora tonkinensis".FITOTERAPIA 99(2014):21-27.