Studies on the toxic effects of La(3+) to Tetrahymena thermophila by microcalorimetry

CORC > 水生生物研究所 > 中科院水生所知识产出（2009年前） > 淡水生态学研究中心 > 期刊论文

	Studies on the toxic effects of La(3+) to Tetrahymena thermophila by microcalorimetry
	Chen Xiaojuan 1,2,3; Feng Weisong 3; Yu Yuhe 3; Wan Chengyan 1,2; Peng Jianhua 1,2
刊名	BIOLOGICAL TRACE ELEMENT RESEARCH
	2008-06-01
卷号	123 期号:1-3 页码:242-249
关键词	La(3+) Tetrahymena thermophila microcalorimetry thermogenic curves inhibition cell growth membrane fluidity
ISSN号	0163-4984
英文摘要	The toxic effects of La(3+) on Tetrahymena thermophila have been studied by microcalorimetry at 28 degrees C. The metabolic rate constant (r) and peak time were linked to the concentration of La(3+). The changes of metabolic rate constant indicated that low-concentration La(3+) (0-75 mg/L) had no significant effects on the metabolism of Tetrahymena cells but high-concentration La(3+) (100-175 mg/L) could inhibit their metabolism. From the results obtained by cell counting and fluorescence depolarization measurements, the inhibition of metabolism resulted from the decrease in cell number and the reduction in cell membrane fluidity. According to the results, it is clear that the metabolic mechanism of Tetrahymena cells has been changed with the addition of high-concentration La(3+). In addition, microcalorimetry of Tetrahymena could be a sensible, easy-to-use, and convenient method for monitoring the potential effects of rare earth elements on cells and the freshwater ecosystem.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biochemistry & Molecular Biology ; Endocrinology & Metabolism
研究领域[WOS]	Biochemistry & Molecular Biology ; Endocrinology & Metabolism
关键词[WOS]	MEMBRANE FLUIDITY ; CELLS ; PHOSPHATIDYLCHOLINE ; PYRIFORMIS ; GROWTH ; IONS
收录类别	SCI
语种	英语
WOS记录号	WOS:000256084000027
公开日期	2015-12-27
内容类型	期刊论文
源URL	[http://ir.ihb.ac.cn/handle/342005/27366]
专题	水生生物研究所_淡水生态学研究中心_期刊论文
作者单位	1.Minist Water Resources, Inst Hydroecol, Wuhan 430079, Peoples R China 2.Chinese Acad Sci, Inst Hydroecol, Wuhan 430079, Peoples R China 3.Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China
推荐引用方式 GB/T 7714	Chen Xiaojuan,Feng Weisong,Yu Yuhe,et al. Studies on the toxic effects of La(3+) to Tetrahymena thermophila by microcalorimetry[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2008,123(1-3):242-249.
APA	Chen Xiaojuan,Feng Weisong,Yu Yuhe,Wan Chengyan,&Peng Jianhua.(2008).Studies on the toxic effects of La(3+) to Tetrahymena thermophila by microcalorimetry.BIOLOGICAL TRACE ELEMENT RESEARCH,123(1-3),242-249.
MLA	Chen Xiaojuan,et al."Studies on the toxic effects of La(3+) to Tetrahymena thermophila by microcalorimetry".BIOLOGICAL TRACE ELEMENT RESEARCH 123.1-3(2008):242-249.