Brain spontaneous functional connectivity and intelligence

	Brain spontaneous functional connectivity and intelligence
	Song, Ming2 ; Zhou, Yuan 2; Li, Jun 2; Liu, Yong2 ; Tian, Lixia 3; Yu, Chunshui 1; Jiang, Tianzi2
刊名	NEUROIMAGE
	2008-07-01
卷号	41 期号:3 页码:1168-1176
关键词	functional MRI (fMRI) intelligence spontaneous brain activity functional connectivity
英文摘要	Many functional imaging studies have been performed to explore the neural basis of intelligence by detecting brain activity changes induced by intelligence-related tasks, such as reasoning or working memory. However, little is known about whether the spontaneous brain activity at rest is relevant to the differences in intelligence. Here, 59 healthy adult subjects (Wechsler Adult Intelligence Scale score, 90-138) were studied with resting state fMRI. We took the bilateral dorsolateral prefrontal cortices (DLPFC) as the seed regions and investigated the correlations across subjects between individual intelligence scores and the strength of the functional connectivity (FC) between the seed regions and other brain regions. We found that the brain regions in which the strength of the FC significantly correlated with intelligence scores were distributed in the frontal, parietal, occipital and limbic lobes. Stepwise linear regression analysis also revealed that the FCs within the frontal lobe and between the frontal and posterior brain regions were both important predictive factors for the differences in intelligence. These findings support a network view of intelligence, as suggested in previous studies. More importantly, our findings suggest that brain activity may be relevant to the differences in intelligence even in the resting state and in the absence of an explicit cognitive demand. This could provide a new perspective for understanding the neural basis of intelligence. (C) 2008 Elsevier Inc. All rights reserved.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]	Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]	GENERAL INTELLIGENCE ; PREFRONTAL CORTEX ; FLUID INTELLIGENCE ; COMPONENT ANALYSIS ; DATA SETS ; FMRI ; NETWORKS ; PERFORMANCE ; ACTIVATION ; SYSTEMS
收录类别	SCI
语种	英语
WOS记录号	WOS:000256271700042
公开日期	2015-12-24
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/9580]
专题	自动化研究所_09年以前成果
作者单位	1.Capital Med Univ, Xuanwu Hosp, Dept Radiol, Beijing 100053, Peoples R China 2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100080, Peoples R China 3.Beijing Jiaotong Univ, Sch Comp & Informat Technol, Dept Biomed Engn, Beijing 100044, Peoples R China
推荐引用方式 GB/T 7714	Song, Ming,Zhou, Yuan,Li, Jun,et al. Brain spontaneous functional connectivity and intelligence[J]. NEUROIMAGE,2008,41(3):1168-1176.
APA	Song, Ming.,Zhou, Yuan.,Li, Jun.,Liu, Yong.,Tian, Lixia.,...&Jiang, Tianzi.(2008).Brain spontaneous functional connectivity and intelligence.NEUROIMAGE,41(3),1168-1176.
MLA	Song, Ming,et al."Brain spontaneous functional connectivity and intelligence".NEUROIMAGE 41.3(2008):1168-1176.