Glucaminium ionic liquid-functionalized stationary phase for the separation of nucleosides in hydrophilic interaction chromatography

CORC > 兰州化学物理研究所 > 中国科学院兰州化学物理研究所 > 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室

	Glucaminium ionic liquid-functionalized stationary phase for the separation of nucleosides in hydrophilic interaction chromatography
	Jiang, Qiong 1; Zhang ML(张明亮)2; Wang XS(王旭生)2 ; Guo Y(郭勇)2 ; Qiu HD(邱洪灯)2 ; Zhang, Shusheng 1; Qiu HD(邱洪灯)
刊名	Analytical and Bioanalytical Chemistry
	2015
卷号	407 期号:25 页码:7667-7672
关键词	Ionic liquid Glucaminium stationary phase Hydrophilic interaction High-performance liquid chromatography
ISSN号	1618-2642
通讯作者	邱洪灯 ; Zhang, Shusheng
英文摘要	A glucaminium-based ionic liquid stationary phase was prepared via facile epoxy-amine reaction and subsequent quaternization. Successful immobilization of glucaminium-based ionic liquid onto silica surface was validated by elemental analysis and infrared spectroscopy. The new stationary phase was evaluated for the separation of nucleosides in hydrophilic interaction liquid chromatography (HILIC). Effects of various factors, such as acetonitrile concentration, salt concentration, pH value, as well as column temperature, on the chromatographic behavior toward nucleosides were studied in detail. The results indicated that this new stationary phase can be used for separation of water-soluble polar substances in HILIC mode. The retention of solutes on the stationary phase was influenced by a mixed-mode retention mechanism with a combination of adsorptive and partitioning interactions.
学科主题	分析化学与药物化学
收录类别	SCI
资助信息	the "Hundred Talents Program" of Chinese Academy Sciences;the National Natural Science Foundation of China (21475142)
语种	英语
WOS记录号	WOS:000361633700012
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/18668]
专题	兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
通讯作者	Qiu HD(邱洪灯)
作者单位	1.Zhengzhou Univ, Dept Chem, Key Lab Chem Biol & Organ Chem Henan, Zhengzhou 450052, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China
推荐引用方式 GB/T 7714	Jiang, Qiong,Zhang ML,Wang XS,et al. Glucaminium ionic liquid-functionalized stationary phase for the separation of nucleosides in hydrophilic interaction chromatography[J]. Analytical and Bioanalytical Chemistry,2015,407(25):7667-7672.
APA	Jiang, Qiong.,Zhang ML.,Wang XS.,Guo Y.,Qiu HD.,...&邱洪灯.(2015).Glucaminium ionic liquid-functionalized stationary phase for the separation of nucleosides in hydrophilic interaction chromatography.Analytical and Bioanalytical Chemistry,407(25),7667-7672.
MLA	Jiang, Qiong,et al."Glucaminium ionic liquid-functionalized stationary phase for the separation of nucleosides in hydrophilic interaction chromatography".Analytical and Bioanalytical Chemistry 407.25(2015):7667-7672.