Chiral separation by counter-current chromatography
Huang XY(黄新异); Di DL(邸多隆); Di DL(邸多隆)
刊名Trends in Analytical Chemistry
2015
卷号67页码:128-133
关键词Biphasic chiral recognition Chiral chromatography Chiral selector Chiral separation Counter-current chromatography Liquid-liquid partition Multiple dual-mode elution Recycling elution mode Separation efficiency Solvent system
ISSN号0165-9936
通讯作者邸多隆
英文摘要Counter-current chromatography (CCC) is a new, efficient, productive chromatographic technique based on continuous liquid-liquid partition. Recently, it attracted more attention in chiral separation due to its high load capacity, cheap liquid stationary phase and low solvent consumption, when compared to traditional chiral separation techniques. This review presents advances and applications of chiral separation using high-speed CCC in recent years. We summarize the major benefits and the limitations of chiral separation by CCC. We introduce in detail some novel methods, which can improve the resolution of enantiomers and are easily achieved on classical CCC apparatus. We also outline challenges and future perspectives in developing chiral separation by CCC.
学科主题分析化学与药物化学
收录类别SCI
资助信息the National Natural Science Foundation of China (NSFC Nos. 20775083;21175142);CAS;the Advanced Bioprocessing Centre at Brunel University, UK
语种英语
WOS记录号WOS:000354149200018
内容类型期刊论文
源URL[http://210.77.64.217/handle/362003/18351]  
专题兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
通讯作者Di DL(邸多隆)
作者单位Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Science, Lanzhou 73000, China
推荐引用方式
GB/T 7714
Huang XY,Di DL,Di DL. Chiral separation by counter-current chromatography[J]. Trends in Analytical Chemistry,2015,67:128-133.
APA Huang XY,Di DL,&邸多隆.(2015).Chiral separation by counter-current chromatography.Trends in Analytical Chemistry,67,128-133.
MLA Huang XY,et al."Chiral separation by counter-current chromatography".Trends in Analytical Chemistry 67(2015):128-133.
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