Optimizing the quadruple-potential waveform for the determination of gentamicin sulfate by high performance liquid chromatography with pulsed electrochemical detection

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Optimizing the quadruple-potential waveform for the determination of gentamicin sulfate by high performance liquid chromatography with pulsed electrochemical detection
	Cai, YQ; Mou, SF
刊名	CHINESE JOURNAL OF CHEMISTRY
	2005
卷号	23 期号:9 页码:1207-1212
关键词	quadruple-potential waveform pulsed electrochemical detection reversed phase ion-pair chromatography gentamicin
英文摘要	In this paper, a quadruple-potential waveform was investigated and optimized for the determination of gentamicin by reversed phase ion-pair chromatography. Instead of a relatively high positive potential, a negative potential was adopted as a potential for the cleaning of gold working electrode. By this way, the formation of gold oxide resulting from the application of high positive potential during the analyte detection and electrode cleaning was greatly reduced, and therefore, the dissolution and recession of gold working electrode was also reduced. The good condition of gold working electrode achieved by this quadruple-potential waveform can help us to obtain a good reproducibility. In order to acquire signal-to-noise ratio as high as possible, several waveform parameters affecting the detection of gentamicin were carefully selected. The analytical method has been applied to the determination of two real gentamicin samples, and good results with low relative standard deviation not more than 4% were obtained.
学科主题	Chemistry
研究领域[WOS]	Chemistry
WOS记录号	WOS:000231723700015
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/23197]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Cai, YQ,Mou, SF. Optimizing the quadruple-potential waveform for the determination of gentamicin sulfate by high performance liquid chromatography with pulsed electrochemical detection[J]. CHINESE JOURNAL OF CHEMISTRY,2005,23(9):1207-1212.
APA	Cai, YQ,&Mou, SF.(2005).Optimizing the quadruple-potential waveform for the determination of gentamicin sulfate by high performance liquid chromatography with pulsed electrochemical detection.CHINESE JOURNAL OF CHEMISTRY,23(9),1207-1212.
MLA	Cai, YQ,et al."Optimizing the quadruple-potential waveform for the determination of gentamicin sulfate by high performance liquid chromatography with pulsed electrochemical detection".CHINESE JOURNAL OF CHEMISTRY 23.9(2005):1207-1212.