Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain
Huang, Xuenian1,3; Lu, Xuefeng1; Li, Yueming2; Li, Xia2; Li, Jian-Jun1
刊名MICROBIAL CELL FACTORIES
2014-08-11
卷号13期号:1页码:1
关键词Itaconic acid Aspergillus terreus Genetic engineering Itaconate titer
英文摘要

Background: Itaconic acid, which has been declared to be one of the most promising and flexible building blocks, is currently used as monomer or co-monomer in the polymer industry, and produced commercially by Aspergillus terreus. However, the production level of itaconic acid hasn't been improved in the past 40 years, and mutagenesis is still the main strategy to improve itaconate productivity. The genetic engineering approach hasn't been applied in industrial A. terreus strains to increase itaconic acid production.

WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biotechnology & Applied Microbiology
研究领域[WOS]Biotechnology & Applied Microbiology
关键词[WOS]FUNCTIONAL-CHARACTERIZATION ; HETEROLOGOUS EXPRESSION ; ESCHERICHIA-COLI ; NIGER ; BIOSYNTHESIS ; PROMOTER ; OVEREXPRESSION ; DECARBOXYLASE ; OPTIMIZATION ; LOVASTATIN
收录类别SCI
语种英语
WOS记录号WOS:000340803600001
内容类型期刊论文
源URL[http://ir.qibebt.ac.cn/handle/337004/6363]  
专题青岛生物能源与过程研究所_微生物代谢工程团队
作者单位1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, Key Lab Biofuels, Qingdao 266101, Peoples R China
2.Qingdao Kehai Biochem Co Ltd, Qingdao 266400, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Huang, Xuenian,Lu, Xuefeng,Li, Yueming,et al. Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain[J]. MICROBIAL CELL FACTORIES,2014,13(1):1.
APA Huang, Xuenian,Lu, Xuefeng,Li, Yueming,Li, Xia,&Li, Jian-Jun.(2014).Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain.MICROBIAL CELL FACTORIES,13(1),1.
MLA Huang, Xuenian,et al."Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain".MICROBIAL CELL FACTORIES 13.1(2014):1.
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