Photosynthetic production of glycerol by a recombinant cyanobacterium
Savakis, Philipp1; Tan, Xiaoming2; Du, Wei1; dos Santos, Filipe Branco1; Lu, Xuefeng2; Hellingwerf, Klaas J.1
刊名JOURNAL OF BIOTECHNOLOGY
2015-02-10
卷号195页码:46-51
关键词Synechocystis Metabolic engineering Cell factory Glycerol
英文摘要Cyanobacteria are prokaryotic organisms capable of oxygenic photosynthesis. Glycerol is an important commodity chemical. Introduction of phosphoglycerol phosphatase 2 from Saccharomyces cerevisiae into the model cyanobacterium Synechocystis sp. PCC6803 resulted in a mutant strain that produced a considerable amount of glycerol from light, water and CO2. Mild salt stress (200 mM NaCl) on the cells led to an increase of the extracellular glycerol concentration of more than 20%. Under these conditions the mutant accumulated glycerol to an extracellular concentration of 14.3 mM after 17 days of culturing. (C) 2014 Elsevier B.V. All rights reserved.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biotechnology & Applied Microbiology
研究领域[WOS]Biotechnology & Applied Microbiology
关键词[WOS]LACTIC-ACID ; PATHWAY ; FERMENTATION ; EXPRESSION ; STRESS ; GPP2P
收录类别SCI
语种英语
WOS记录号WOS:000348839500007
公开日期2015-12-24
内容类型期刊论文
源URL[http://ir.qibebt.ac.cn/handle/337004/6076]  
专题青岛生物能源与过程研究所_微生物代谢工程团队
作者单位1.Univ Amsterdam, Swammerdam Inst Life Sci, Mol Microbial Physiol Grp, Amsterdam, Netherlands
2.Chinese Acad Sci, Shandong Prov Key Lab Energy Genet, Qingdao Inst Bioenergy & Bioproc Technol, Lab Biofuels, Beijing 100864, Peoples R China
推荐引用方式
GB/T 7714
Savakis, Philipp,Tan, Xiaoming,Du, Wei,et al. Photosynthetic production of glycerol by a recombinant cyanobacterium[J]. JOURNAL OF BIOTECHNOLOGY,2015,195:46-51.
APA Savakis, Philipp,Tan, Xiaoming,Du, Wei,dos Santos, Filipe Branco,Lu, Xuefeng,&Hellingwerf, Klaas J..(2015).Photosynthetic production of glycerol by a recombinant cyanobacterium.JOURNAL OF BIOTECHNOLOGY,195,46-51.
MLA Savakis, Philipp,et al."Photosynthetic production of glycerol by a recombinant cyanobacterium".JOURNAL OF BIOTECHNOLOGY 195(2015):46-51.
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