The neuroplastic effect of working memory training in healthy volunteers and patients with schizophrenia: Implications for cognitive rehabilitation

CORC > 心理研究所 > 中国科学院心理研究所 > 中国科学院心理健康重点实验室

	The neuroplastic effect of working memory training in healthy volunteers and patients with schizophrenia: Implications for cognitive rehabilitation
	Li, Xu1,2 ; Xiao, Ya-hui 1,2; Zhao, Qing3,4 ; Leung, Ada W. W.5,6,7; Cheung, Eric F. C.8; Chan, Raymond C. K.1
刊名	NEUROPSYCHOLOGIA
	2015-08-01
卷号	75 期号:0 页码:149-162
关键词	Working memory Training Imaging Activation likelihood estimation meta-analysis Schizophrenia
ISSN号	0028-3932
英文摘要	We conducted an activation likelihood estimation (ALE) meta-analysis to quantitatively review the existing working memory (WM) training studies that investigated neural activation changes both in healthy individuals and patients with schizophrenia. ALE analysis of studies in healthy individuals indicates a widespread distribution of activation changes with WM training in the frontal and parietal regions, especially the dorsolateral prefrontal cortex, the medial frontal cortex and the precuneus, as well as subcortical regions such as the insula and the striatum. WM training is also accompanied by activation changes in patients with schizophrenia, mainly in the dorsolateral prefrontal cortex, the precuneus and the fusiform gyrus. Our results demonstrate that WM training is accompanied by changes in neural activation patterns in healthy individuals, which may provide the basis for understanding neuroplastic changes in patients with schizophrenia. (C) 2015 Elsevier Ltd. All rights reserved.
收录类别	SSCI
语种	英语
WOS记录号	WOS:000360596700015
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/15229]
专题	心理研究所_中国科学院心理健康重点实验室
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Griffith Univ, Sch Appl Psychol, Brisbane, Qld 4111, Australia 4.Griffith Univ, Griffith Hlth Inst, Behav Basis Hlth Program, Brisbane, Qld 4111, Australia 5.Univ Alberta, Dept Occupat Therapy, Edmonton, AB, Canada 6.Univ Alberta, Ctr Neurosci, Edmonton, AB, Canada 7.Baycrest Ctr Geriatr Care, Rotman Res Inst, Toronto, ON, Canada 8.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Li, Xu,Xiao, Ya-hui,Zhao, Qing,et al. The neuroplastic effect of working memory training in healthy volunteers and patients with schizophrenia: Implications for cognitive rehabilitation[J]. NEUROPSYCHOLOGIA,2015,75(0):149-162.
APA	Li, Xu,Xiao, Ya-hui,Zhao, Qing,Leung, Ada W. W.,Cheung, Eric F. C.,&Chan, Raymond C. K..(2015).The neuroplastic effect of working memory training in healthy volunteers and patients with schizophrenia: Implications for cognitive rehabilitation.NEUROPSYCHOLOGIA,75(0),149-162.
MLA	Li, Xu,et al."The neuroplastic effect of working memory training in healthy volunteers and patients with schizophrenia: Implications for cognitive rehabilitation".NEUROPSYCHOLOGIA 75.0(2015):149-162.